dagblog - Comments for "946 Genetic Variants of hCoV-19" http://dagblog.com/link/946-genetic-variants-hcov-19-30527 Comments for "946 Genetic Variants of hCoV-19" en Most drugs tested are not new http://dagblog.com/comment/278364#comment-278364 <a id="comment-278364"></a> <p><em>In reply to <a href="http://dagblog.com/comment/278356#comment-278356">Thanks for these links.</a></em></p> <div class="field field-name-comment-body field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Most drugs tested are not new, so likely little profit there. </p> <p>A big motivator here is the "charitable" objective to restore life to some level of normal. A research team or company that can do that will achieve world wide notoriety and approbation. It's a professional scientific race, a challenge unlike anything the modern world has ever experienced.</p> </div></div></div> Mon, 23 Mar 2020 06:44:10 +0000 NCD comment 278364 at http://dagblog.com Thanks for these links. http://dagblog.com/comment/278356#comment-278356 <a id="comment-278356"></a> <p><em>In reply to <a href="http://dagblog.com/link/946-genetic-variants-hcov-19-30527">946 Genetic Variants of hCoV-19</a></em></p> <div class="field field-name-comment-body field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Thanks for these links.</p> <p>For this reason I have been also been trying to pay attention to development of better treatments for symptoms, specifically the extreme suffocation style pneumonia that is the main killer.</p> <p>After all, this is what happened with AIDS, there is no cure per se, just more and better treatments over time (nor do we have a cure for the common cold.)</p> <p>You know I am totally for taking all the profit motive out of <em>the actual practice of medicine.</em> As the practice of medicine is a actually more of an art not a science and providers are supposed to be professionals, not profit seeking.</p> <p>BUT the problem here really brings close to home how helpful and inspirational the profit motive can be in development of drugs and devices. Yes, the downside is this leaves some diseases to be "orphans" because there aren't enough sufferers for profit. And I myself tend to trust research papers on new treatments from the Brits because not the least of which they will research things that are already inexpensively available.  At the same time, and despite Jonas Salk's famous charitable attitude, there's no motivator like possibly being able to make a fortune off a good treatment where none exists.</p> <p>Don't know how to square this. How do you make new treatment inventions profitable while at the same time keep a non-profit medical system and keep costs of treatments down under government controlled pricing....</p> </div></div></div> Mon, 23 Mar 2020 05:14:54 +0000 artappraiser comment 278356 at http://dagblog.com See also - 'Why Testing for http://dagblog.com/comment/278355#comment-278355 <a id="comment-278355"></a> <p><em>In reply to <a href="http://dagblog.com/link/946-genetic-variants-hcov-19-30527">946 Genetic Variants of hCoV-19</a></em></p> <div class="field field-name-comment-body field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>See also - 'Why Testing for Coronavirus Antibodies Will Matter.'</p> <p>" ... If you go to <a href="http://www.gisaid.org/">www.gisaid.org</a>, an open-source repository of all genetic strains of the COVID-19 virus, you’ll see that we already have 683 fully sequenced versions of the virus. That’s not HIV-level of mutation, but it’s a lot!</p> <p>So that makes me worried that a year from now, when we finally have something that looks promising and we’re ready to go into large clinical trials, there may be enough strains that it has to be treated like the annual flu vaccine, where you actually get five or six viral vaccines at once because there’s so many different strains of flu out there. I’m not at all optimistic that we’re going to have a vaccine in a year or even a year and a half. I think it’s going to be far more complicated ... "</p> <p>   <a href="https://nymag.com/intelligencer/2020/03/why-testing-for-coronavirus-antibodies-will-matter.html#comments">link</a></p> </div></div></div> Mon, 23 Mar 2020 04:27:57 +0000 NCD comment 278355 at http://dagblog.com