This is very worrisome. Among recovered former #COVID19 cases, “nearly a third had unexpectedly low levels of antibodies. In some cases, antibodies could not be detected at all.” https://t.co/VEwTJWOJD2
3) Antibodies are generated by the immune system and have unique chemical structures to inhibit specific pathogens. The coronavirus antibody intercepts the spike protein on the viral envelope to prevent it from binding with human cells. #COVID19
4) “researchers said they were surprised to find that the antibody “titer” value in about a third of the patients was less than 500, a level that might be too low to provide protection.” #COVID19
5) “About 30 per cent of patients failed to develop high titers of neutralising antibodies after #Covid19 infection. However, the disease duration of these patients compared to others was similar," they said.
6) “The team also found that antibody levels rose with age, with people in the 60-85 age group displaying more than three times the amount of antibodies as people in the 15-39 age group.” #COVID19
7) low amounts of antibodies could affect herd immunity, resistance to the disease among the general population to stop its spread. “What this will mean to herd immunity will require more data from other parts of the world,” Professor Huang Jinghe, leader of team, said. #COVID19
8) “Vaccine developers may need to pay particular attention to these patients,” Huang said. If the real virus could not induce antibody response, the weakened version in the vaccine might not work in these patients either. #COVID19
9) The researchers also found that #Covid19 antibody could bind with a distantly related strain SARS-1 in 2003. But the binding could not suppress SARS-1 virus replication in cells, dashing hopes of developing a vaccine for two or even more coronavirus strains at once.
10) “Who knows whether #COVID19 will become something like seasonal flu, or chronic disease like hepatitis B, or just vanish like Sars?” he said. “Up till now we still lack imagination [to tell].” Translation: now it’s looks worse than before.
No, not concerning. Only the covid-19 surface spiked protein was tested, which is unreliable. The more reliable nucleocapsid protein wasn’t. And u didn’t link the original submission, just a reporter’s interpretation. Here u go, but it’s only an abstract.https://t.co/pErcHibx7J
⚠️PLASMA TRANSFUSION: Whoa - plasma from recovered #COVID19 patients tested in 10 severe cases showed that 1 dose (200 mL) of CP could increase or maintain the neutralizing antibodies at a high level, symptoms improved in 3 days, w/ viral load gone in 7 d. https://t.co/y0fUTmJbGs
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by artappraiser on Wed, 04/08/2020 - 8:00pm
This is where clinical trials and research need to play out in their courses despite our desire to whip the horses to make them run faster.
There are reports like these: https://www.fiercebiotech.com/medtech/current-covid-19-antibody-tests-aren-t-accurate-enough-for-mass-screening-say-oxford
I was hoping that aggressively moving forward with anti-body tests would not be problematic but it is.
by moat on Wed, 04/08/2020 - 8:18pm
by artappraiser on Wed, 04/08/2020 - 9:33pm
Your friend, the bat,,,
Y'know, DoubleA, bats are extremely important overall for insect control and whatnot.
That said, they get a bad jacket (partly that vampire thingy) and people harbor vague hostility.
That picture does not help...
by jollyroger on Wed, 04/08/2020 - 11:03pm
It wasn't Batman that wanted to see the world burn - it was The Joker.
by PeraclesPlease on Thu, 04/09/2020 - 3:55am
I note bats do seem to have a P.R. campaign on Twitter to push cute images of them so that stock photo usage might quit the stereotyping:
by artappraiser on Thu, 04/09/2020 - 4:31pm
Glowing blue eyes are not conducive to cuddling...
by jollyroger on Thu, 04/09/2020 - 4:32pm
your friend, the other bat...
6 new coronaviruses discovered in bats
https://www.livescience.com/6-new-coronaviruses-found-bats.html?utm_sour...
by jollyroger on Fri, 04/10/2020 - 2:13pm
and so very ugly to boot
by artappraiser on Fri, 04/10/2020 - 5:16pm
and so very ugly to boot
Edit to add: yes so creepy I posted it twice
by artappraiser on Fri, 04/10/2020 - 5:17pm
just for you, Rog,
by artappraiser on Fri, 04/17/2020 - 4:41am