Lost his wife and mother in 1 day, makes me think of the parallels to today, wealthy but still vulnerable to the crowding conditions and pandemics that don't spare the rich.
Was there a huge surge in rejection for typhoid quarantines, outbursts that personal freedom was more important, or it still wasn't that much of a concept at that time?
In any case, it likely had a big impact on Teddy's later renowned efforts that made him larger than life.